New results are presented on interfacial patterns observed for air and water flowing in horizontal 2.54 and 9.53 cm pipelines close to atmospheric conditions. This work differs from previous studies in that measurements of pressure fluctuations at two locations separated in the streamwise direction are used to detect slugs. The liquid flow needed to initiate slugs at low gas velocities is strongly affected by pipe diameter and appears to depend on a linear instability. At high gas velocities the transition is approximately independent of pipe diameter and is explained by a nonlinear mechanism associated with the coalescence of roll waves. The initiation of slugs in the annular flow regime is determined to occur at much lower liquid flows than had been reported by previous investigators. The transition from stratified to annular flow is different in smaller-diameter pipes Basket Blazer Femme Grise than in larger pipes because wave wetting plays a more important role.
A family of loci homologous to the EGF-like portion of Notch, a gene involved in neurogenesis, have been identified in D. melanogaster. The sequence, spatial, and temporal distribution of both RNA and protein of one of these loci suggest a possible role in the development of the central nervous system (CNS). In situ hybridization and antibody staining of embryos show initial localization in cells along the midline of the neuroepithelium. High level expression is restricted in the developing embryo to a subset of six midline glial cells abutting growing axons. Extracellular localization is suggested by the presence of EGF-like repeats in the deduced protein sequence and antibody staining. Cytological, immunocytochemical, genetic, and molecular data show that this gene corresponds to the slit locus. Mutations in this locus result in the collapse of the Blazer Nike Homme Solde regular Chaussure Nike Blazer scaffold of commissural and longitudinal axon tracts in the embryonic central nervous system.
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